Immunohistochemical Study on Breast Cancer.

Immunohistochemical characteristics of basal-like breast cancer

Basal-like breast cancer (BLBC) occurs mainly in young patients. It is characterized by an aggressive clinical outcome, presence of distant metastases, particularly within the first five years of the disease, bad prognosis and relatively high mortality. Recently greater interest of scientists in this subtype of breast cancer has been observed. Despite such many well-known potential biomarkers o...

Immunohistochemical Differentiation of Triple Negative Breast Cancer.

Based on immunohistochemical staining for the basal markers cytokeratin 5/6 (CK 5/6), cytokeratin 14 (CK 14) and P-cadherin, triple negative tumors (TNT) are divided into two groups: 1) basal-like (BL) positive for one or all three markers; and 2) non basal-like (NBL) negative for all three markers. Even though the different origin of the cells of these two types of tumors implies different bio...

Study on the association of Epstein - Barr virus with breast cancer in Khorramabad breast cancer patients, Iran

Background: Breast cancer is one of the most common malignancies in the world, and early diagnosis of this cancer is a key factor in its treatment. This cancer is a multi-stage disease, in which viruses can play a role. EBV is known as an important factor in the development of some human cancers. Therefore, this study was conducted to determine the relationship between Epstein-Barr virus, EBV, ...

Cytoplasmic Her2/neu immunohistochemical staining in breast cancer; From a molecular point of view

SHIRAZ BREAST CANCER STUDY PART II: SCREENING MAMMOGRAPHY IN A OPULATIONBASED BREAST CANCER SURVEY

The purpose of this study was to assess the detection rate of mammography in breast cancer and the attendance rate in response to the call for screening mammography in females before the development of symptoms. One-thousand four-hundred and thirty-eight women over 35 years of age who had no complaint and had normal breast examinations were called for mammography. Out of the 10,000 women u...